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Unexplained Constipation (Ages 6 – 17)

Medical Condition



PMG Research of Knoxville






Constipation in children and adolescents can be a struggle for parents to treat. In addition to pain and discomfort when using the bathroom, missed school and increased doctors’ visits can interrupt a child’s quality of life. 

A research study is evaluating a medication that is FDA-approved for adult constipation that may relieve symptoms of unexplained constipation in children and adolescents. 

This research study may be an option if your child: 
Has been experiencing unexplained constipation for the past 2 months
Weighs at least 39.6 lbs.
Does not have celiac disease or inflammatory bowel disease
Other criteria apply.  

Qualified participants will receive all study-related care and study medication or placebo at no cost.



Patient Commitment Duration

Approximately 4.5 months

Patient Compensation

Financial compensation may be provided for time and travel expenses.  

Number of visits in study

Approximately 8 clinic visits

Apply for this Study Now