Medical Advisory Board

As an organization committed to providing unparalleled service to our clients: patient volunteers, the pharmaceutical industry, and our healthcare partners, we greatly value the physician investigator as a research patient advocate and also value the physician investigator’s perspective of both the Pharma and health care landscape.  Therefore, we have established a PMG Research Medical Advisory Board to provide guidance to PMG Research with two primary objectives:

  • Research Patient Engagement and Patient Compliance
  • Promoting Shared Value Between PMG Research and our Health Care Institutions and Physician Provider Relationships to Optimize Clinical Research as a Care Option

The Medical Advisory Board will convene on a quarterly basis to advise PMG Research with respect to select patient-focused strategic initiatives, regulatory and health care policy, and physician and health care engagement to better advance bringing the right trials to the right patients.



Jennifer ByrneDr. John Rubino, MD


Dr. Rubino completed his undergraduate and medical degrees at the University of Connecticut. After his residency at the University of North Carolina at Chapel Hill he joined Raleigh Medical Group in 1986. There, in 1989, he was instrumental in forming their two clinical research sites now known as PMG Research of Raleigh and PMG Research of Cary. Since 2005, Raleigh Medical Group, a 33 physician internal medicine group, has successfully integrated clinical research into their practice with PMG. For over 20 years, Dr. Rubino has been principal investigator in over 600 clinical trials and has served in various consultancy capacities to the research industry. He is past President of Key IPA and presently Vice President of WakeMed Key Community Care, which is the largest Accountable Care Organization in North Carolina. He also serves as the Team Physician for North Carolina State University Athletics.

Dr. Rubino looks forward to participating in the Medical Advisory Board to bring forth the value of clinical research to patients, pharma, and the healthcare industry while improving the research process for all participants.

Charles HauserDr. Robert Holmes, MD


Dr. Holmes has been a principal investigator at PMG of Winston-Salem since 1997. After graduating from University of Texas Southwestern Medical School in Dallas, he completed internal medicine and gastroenterology/hepatology training at the University of Michigan. He practices at Gastroenterology Associates of the Piedmont (GAP), a practice which has been independent for more than 50 years.

Dr. Holmes believes strongly in the importance of clinical research, participating in multiple trials which have led to breakthroughs in inflammatory bowel disease, irritable bowel syndrome, colon cancer screening, chronic idiopathic constipation, as well as chronic liver disease, to name but a few. He believes clinical research is a valuable and safe care option for patients with acute and chronic illnesses.

Dr. Holmes is affiliated with Novant Health and serves as co-chair of the Pharmacy and Therapeutics Committee as well as the Director of Nutritional Support at Forsyth Medical Center. He looks forward to providing guidance and insight on the PMG Research Medical Advisory Board to further evolve the role of clinical research in patient care.

Joel LanikDr. Douglas Lee, MD


Dr. Lee graduated from East Carolina School of Medicine in Greenville, NC, where he also completed his internship and residency. During medical school, Dr. Lee spent a year conducting bench research as part of the Howard Hughes Research Scholars Program at National Institutes of Health in Bethesda, MD. His fellowship was performed at Johns Hopkins in Baltimore, MD. Dr. Lee is certified in Pulmonary Medicine, Sleep Medicine, and Critical Care. He practices at Wilmington Health, a multi-specialty clinic with integrated primary care providers, allowing for a comprehensive and coordinated approach to patient care. Dr. Lee is also Medical Director of the Wilmington Sleep Disorders Center and the Atlantic Sleep Center; he is Clinical Assistant Professor, Department of Medicine, SEHAC, UNC School of Medicine.

Dr. Lee has been conducting research with PMG Research since 2008, and has been Principal Investigator on over 30 trials including but not limited to: COPD, Asthma, Sleep Apnea, DVT, Restless Leg Syndrome, Community Acquired Bacterial Pneumonia, Weight Loss, and Sepsis. Dr. Lee looks forward to his membership on the Medical Advisory Board in order to further clinical research as a care option for patients while elevating its value to the pharmaceutical and healthcare industries.